Courtesy of www.inspirehealth.ca
Vitamin D can make a substantial difference in cancer prevention and 
survival outcomes, yet many Canadians have sub-optimal levels of Vitamin
 D. This is even more prevalent during the winter months when there are 
fewer hours of sunlight. In an effort to create awareness about the need
 for and benefit of Vitamin D, InspireHealth has named November 2 
Vitamin D Day, and will be offering a free national webinar on that 
afternoon to coincide with the initiative.
Vitamin D helps boost the immune system, and also has the added 
benefit of substantially reducing the risk of heart disease, diabetes, 
strokes, MS, depression and even the flu. Vitamin D is an essential 
component of healthy living, and can easily be incorporated into 
everyone’s lifestyle. The national webinar will be this Friday, November
 2nd at 12 noon PST and will provide a forum to discuss and offer 
information on its benefits.
“We simply have to do more to engage people in this simple, safe 
approach to cancer prevention and treatment,” states Dr. Hal Gunn MD, 
CEO and co-founder of InspireHealth. “The time has arrived for 
nationally coordinated action to substantially increase intake of 
vitamin D,” he added. Last year, over 20 cities and municipalities 
across Canada officially recognized Vitamin D day, and this year the 
number is expected to rise.
The increasing momentum behind this awareness campaign is strongly 
supported by research evidence. A study published in the Annals of 
Epidemiology concluded that supplementation with vitamin D could prevent
 approximately 58,000 new cases of breast cancer and 49,000 cases of 
colorectal cancer in North America each year. Moreover, blood vitamin D 
level at the time of diagnosis for breast and colon cancer is highly 
correlated with survival.
The benefits of Vitamin D are substantial, and may be surprising to 
discover. Everyone is invited to learn more at the free webinar to mark 
the occasion of Vitamin D Day. Dr. Cletus D’Souza, Director of Research 
at InspireHealth, will discuss the benefits and requirements of Vitamin D
 for cancer prevention and overall health. Sign up is available through 
the following link: inspirehealth.ca/vitamind
Learn More:
Visit InspireHealth at www.inspirehealth.ca
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 Key Ingredients Found in nutraMetrix Isotonix® Vitamin D with K2:  
Vitamin D3 (Cholecalciferol) 5000 IU  Vitamin
 D is a fat-soluble vitamin that is found in some foods and endogenously
 produced when sunlight strikes the skin and activates vitamin D 
synthesis. Vitamin D promotes the efficient intestinal absorption of 
calcium, primarily in the duodenum and jejunum by supporting the 
synthesis of calcium-binding proteins to promote normal calcium 
absorption and retention. Vitamin D also promotes the normal formation 
of bone and normal bone growth and bone remodeling by osteoblasts and 
osteoclasts. Vitamin D deficiency can be caused by factors such as lack 
of exposure to sunlight, reduced skin synthesis of vitamin D, lower 
dietary intake, impaired intestinal absorption and reduced metabolism to
 active forms of vitamin D by the kidneys, all of which increase with 
aging. Deficiency has been linked to numerous health concerns, and 
insufficient levels of this vitamin are associated with weak bones and  
muscle weakness. In addition to promoting strong bones, vitamin D also 
has other roles in health, including supporting the body’s normal 
modulation of neuromuscular function and immune function. Vitamin D has 
been shown to support immune-modulation, and it is thought that 
supplementation promotes immune health by promoting the body’s normal 
regulation of T-cell function. In reference to cellular health, vitamin D
 supports the modulation of many genes that are responsible for encoding
 proteins that regulate normal cell cycle activity. Vitamin D levels 
have been strongly correlated to healthy cells. Lastly, through its 
interaction with VDR (vitamin D receptor), vitamin D supports the 
healthy expression of the gene encoding renin, thus helping to maintain 
healthy blood pressure.*  
 
Vitamin K2 45 mcg Vitamin
 K is a fat-soluble vitamin found in meat, eggs, dairy and natto. 
Although a fat-soluble vitamin, the body stores very little K2, and its 
stores are rapidly depleted without regular dietary intake. Natural 
vitamin K2, also known as menaquinone-7 (MK-7), is the most bioavailable
 form of K2 and has the longest half-life in the blood of any form of 
vitamin K. The Japanese soy food natto is particularly rich in 
menaquinone-7 (MK-7). Studies of natto consumption in Japan have linked 
menaquinone-7 to bone and cardiovascular health. The correlation of 
vitamin K to cardiovascular and bone health directly focuses on 
supporting proper calcium utilization, whereby adequate metabolism of 
calcium supports arterial and bone health. This is often referred to as 
the calcium paradox. The calcium paradox is explained simply as getting 
calcium in the right place (i.e., into the bone structures instead of 
the arterial vessel walls.) These events are dependent upon the 
synthesis of the vitamin K-dependent proteins osteocalcin and matrix Gla
 protein in a process called carboxylation. The carboxylation of these 
proteins is a post-translational step; that is, osteocalcin and matrix 
Gla protein are translated from their respective messenger RNA and then 
modified by enzymes to the active forms. These carboxylated forms 
support the healthy binding and releasing of calcium. This reaction is 
essential for optimal and healthy utilization of calcium. Vitamin K2 
promotes the synthesis of proteins involved with calcium utilization, 
thereby supporting bone retention and arterial health. While Vitamin D 
supports the healthy regulation and synthesis of osteocalcin, the 
mineral-binding capacity of this protein requires vitamin K-dependent 
carboxylation and is thought to be related to bone mineralization. Gas6 
is a vitamin K-dependent protein found throughout the nervous system, as
 well in the heart, lungs, stomach, kidneys and cartilage. Although the 
exact mechanism of its action has not been determined, Gas6 appears to 
be a cellular growth regulator involved in cellular activities such as 
cell adhesion, cell proliferation and protection against apoptosis.* 
 
 
What Makes nutraMetrix Isotonix® Vitamin D with K2 Unique? 
nutraMetrix
 Isotonix Vitamin D with K2 contains vitamin D3, the metabolically 
active form of vitamin D, along with vitamin K2, a form of vitamin K 
which supports vascular health and calcium utilization. Vitamin D plays 
an important role in bone health, heart health and immune support, while
 working with vitamin K to support normal absorption of calcium and 
promote healthy arteries. nutraMetrix Isotonix Vitamin D is the first of
 its kind to deliver both of these powerful vitamins with isotonic 
delivery. 
 
Vitamin
 K is included in nutraMetrix Isotonix Vitamin D with K2 because of its 
unique partnership with vitamin D. Vitamins K and D work together to 
support calcium absorption and utilization. Vitamin K supports the 
normal delivery of calcium to the bones and promotes healthy arteries. 
At
 least two naturally-occurring forms of vitamin K have been identified 
and are known as K1 and K2. While there are many similarities between 
these two forms of vitamin K, they are distinguished by their important 
differences. The most significant difference between K1 and K2 is their 
chemical structure which results in different pharmacokinetic 
properties. Vitamin K1 is retained primarily in the liver where, at high
 doses, it may interfere with the action of warfarin and other 
anticoagulant medications.   
 
Vitamin
 K2 has a different mechanism of action. It is transported primarily to 
bones and blood vessels. Vitamin K2 helps to maintain bone mass, support
 calcium utilization and promote elasticity of blood vessels.    
 
Some
 studies have concluded that vitamin K2 does not interfere with 
anticoagulant medications.* However, most products containing vitamin K 
(including K1 and/or K2) warn users taking anticoagulants not to take 
the product. If you are currently taking warfarin or another 
anticoagulant medication, you should consult your physician before 
taking any product containing vitamin K1 or K2. 
 
Isotonix
 dietary supplements are delivered in an isotonic solution. This means 
that the body has less work to do to obtain maximum absorption of the 
nutrients. The isotonic state of the suspension allows nutrients to pass
 directly into the small intestine and rapidly absorb into the 
bloodstream. With Isotonix products, little nutritive value is lost, 
making the absorption of nutrients highly efficient while delivering 
maximum results. 
 
 Frequently Asked Questions about nutraMetrix Isotonix® Vitamin D with K2: 
Why is vitamin K included in nutraMetrix Isotonix Vitamin D with K2? Vitamin
 K is included in this product because of its unique partnership with 
vitamin D. Vitamins K and D work together to promote healthy calcium 
absorption and utilization. Vitamin K supports the delivery of calcium 
to the bones and helps maintain arterial health.*   
Is nutraMetrix Isotonix Vitamin D with K2 safe for people on anticoagulant medications?Some
 studies have concluded that vitamin K2 does not interfere with 
anticoagulant medications. However, most products containing vitamin K 
(including K1 and/or K2) warn users taking anticoagulants not to take 
the product. If you are currently taking warfarin or another 
anticoagulant medication, you should consult your physician before 
taking any product containing vitamin K1 or K2. 
 
How do I take nutraMetrix Isotonix Vitamin D with K2? Mix one capful of Isotonix Vitamin D with K2 with 2 ounces of water. Take one serving daily. 
 
Is it safe to take more than 1 serving of this product daily? One
 serving daily of Isotonix Vitamin D with K2 is recommended. Check with 
your physician before taking additional daily servings of this product. 
 
Is there a toxicity level for vitamin D? The
 recommended daily Upper Limit for vitamin D is 10,000 IU, however, 
safety studies indicate that up to 40,000 IU may be safe for most 
people. If you wish to take more than one daily serving of this product,
 you should check with your physician. 
 
What are dietary sources of vitamin D?  Foods rich in vitamin D include cod liver oil, salmon, mackerel and tuna. 
 
 
 
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