Showing posts with label Alzheimer's Disease. Show all posts
Showing posts with label Alzheimer's Disease. Show all posts

Saturday, December 6, 2014

600 Reasons Turmeric May Be The World’s Most Important Herb

courtesy of GreenMedInfo.com

There is a medicinal spice so timelessly interwoven with the origins of human culture and metabolism, so thoroughly supported by modern scientific inquiry, as to be unparalleled in its proven value to human health and well-being.

Indeed, turmeric turns the entire drug-based medical model on its head.  Instead of causing far more side effects than therapeutic ones, as is the case for most patented pharmaceutical medications, turmeric possesses hundreds of potential side benefits, having been empirically demonstrated to positively modulate over 160 different physiological pathways in the mammalian body.

While no food or herb is right for everyone, and everything has the potential for unintended, adverse side effects, turmeric is truly unique in its exceptionally high margin of safety vis-à-vis the drugs it has been compared with, e.g. hydrocortisone, ibuprofen, chemotherapy agents. Furthermore, nothing within the modern-day pharmaceutical armamentarium comes even remotely close to turmeric’s 6,000 year track record of safe use in Ayurvedic medicine.[1]

Despite its vast potential for alleviating human suffering, turmeric will likely never receive the FDA stamp of approval, due to its lack of exclusivity, patentability and therefore profitability. Truth be told, the FDA’s “gold standard” for proving the value of a prospective medicinal substance betrays the age old aphorism: “he who owns the gold makes the rules,” and unless an investor is willing to risk losing the 800+ million dollars that must be spent upfront, the FDA-required multi-phased double-blind, randomized clinical trials will not occur. For additional details on this rather seedy arrangement read our article on the topic: Why The Law Forbids The Medicinal Use of Natural Substances.

GreenMedInfo.com has reviewed over 5,000 study abstracts from the National Library of Medicine’s bibliographic database known as MEDLINE and have discovered over 600 potential health benefits of turmeric, and/or its primary polyphenol known as curcumin. These can be viewed on our turmeric research page which is dedicated to disseminating the research on the topic to a larger audience.

Some of the most amazing demonstrated properties include:
  • Destroying Multi-Drug Resistant Cancer
  • Destroying Cancer Stem Cells (arguably, the root of all cancer)
  • Protecting Against Radiation-Induced Damage
  • Reducing Unhealthy Levels of Inflammation
  • Protecting Against Heavy Metal Toxicity
  • Preventing and Reversing Alzheimer’s Disease Associated Pathologies
Again, what is so amazing is not that turmeric may have value in dozens of health conditions simultaneously, or that it may improve conditions that are completely resistant to conventional treatment, but that there are over six hundred additional health conditions it may also be valuable in preventing and/or treating. Consider also the fact that turmeric grows freely on the Earth, and you will understand why its very existence threatens billions of dollars in pharmaceutical industry revenue.


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Curcumin Extreme


Why Curcumin Extreme!

Curcumin Extreme


There are many curcumin products on the market, but Curcumin Extreme with BCM-95® has superior bioavailability and absorption. BCM-95 contains the natural spectrum of the turmeric rhizome and is 100 percent natural. Curcumin Extreme promotes liver detoxification, promotes healthy glutathione levels and normal cellular regeneration. Taking Curcumin Extreme every day can help detoxify impurities in your body that build up over time.*
Curcumin Extreme also includes 167 mg of broccoli seed extract, a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of Phase II liver detoxification enzymes, including glutathione synthase, heme-oxygenase and catalase. Sulforaphanes also support gene transcription, the process by which genetic information is copied from DNA to RNA. They also support the body’s natural defense systems. Glutathione is the master antioxidant in the human body, which serves to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. Furthermore, glutathione recycles vitamins C and E, which are also powerful antioxidants.*

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.


Eat Well, Exercise, and Supplement Intelligently with
Orlampa Health
www.orlampahealth.com
727.492.8212



Monday, October 15, 2012

Research finds Vitamin C, beta-carotene link to Alzheimer’s

Research finds Vitamin C, beta-carotene link to Alzheimer’s


Alzheimer’s disease is one of the most feared and devastating diseases that all generations face as they age. Researchers have been unable to pinpoint a cause for Alzheimer’s disease but often attribute it to a combination of genetics, lifestyle and environmental factors that affect the brain over time. There has been so much speculation as to what causes Alzheimer’s disease, however, it is still not yet fully understood.
Recent research has revealed that lower concentrations of vitamin C and beta-carotene in the blood may heighten the risk of developing Alzheimer’s disease in person’s aged 65 to 90 years of age. A study by Professor Gabriele Nagel and Neurologist Professor Christine von Arnim found that these two nutrients were lacking in certain patients who took part in the study:
Antioxidants may prevent the onset [of] Alzheimer’s disease as high dietary intake of vitamin C and E were reported to be associated with lower risk of the disease. We found that blood vitamin C and B-carotene concentrations were significantly lower in demented than in control persons even after adjusting for school education, intake of dietary supplements, smoking habits, body mass index, and alcohol consumption.
Only 5% of the time is Alzheimer’s Disease caused by specific genetic changes that guarantee debilitation. You can begin to reduce your risk of developing this disease with a healthy diet and increasing your vitamin C and beta-carotene antioxidant intakes. Adding these supplements to your daily diet might lower your risk of developing the disease later in life.

Tuesday, October 2, 2012

Merck's Statin Drug Found No Better Than Coconut Water

                                         FAIL: Merck's Statin Drug Found No Better Than Coconut Water
In a 2008 study published in the journal Food Chemistry & Toxicology titled, "Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet,"1 the beverage coconut water was found as effective as a popular cholesterol-lowering drug in positively modulating blood lipid levels in rats.

The conclusion of the study was as follows:

Coconut water has lipid lowering effect similar to the drug lovastatin in rats fed fat-cholesterol enriched diet.
Studies like this, of course, will never make it to the level of the multi-phased human clinical trials necessary to gain FDA drug approval, owing to one simple fact: coconut water is not patentable, and therefore will not provide market exclusivity or the return on investment necessary to capitalize such a venture. Consider that, on average, over 800 million dollars is spent upfront on developing and testing each new drug intended for FDA approval.

Statin Drugs: Defrauding the Public of Their Money & Health

When the water of a coconut is at least as effective as the drug that started the "statin revolution" in 1987 - Merck's branded lovastatin extract known as Mevacor - you know that the 30 billion dollar statin drug industry is based on a fundamentally erroneous premise: namely, that synthetic patentable chemicals are superior to natural ones, and therefore can be sold for usuriously high mark-ups.
Unfortunately the statin drug industry is not only defrauding people of their money, but also their health. As we reported in a previous post, the Journal of Clinical Cardiology in 2009 confirmed that these drugs weaken the heart muscle. Newer research indicates that statins may also be accelerating arterial calcification in susceptible individuals.
Moreover, we have identified over 300 unintended, adverse effects of statin drug use, with the top 20 listed below:
Statin Drugs

Beyond the "Lipid Hypothesis"

While lowering cholesterol is not a priority for me, as I am not a "lipid hypothesis" convert -- to the contrary, I see the clear harms associated with low cholesterol --  people who are convinced that lowering cholesterol and/or lipoproteins reduces cardiovascular disease progression and/or cardiac mortality should at least be well informed as to the natural evidence-based alternatives that exist to drugs.
After all, anything would be more reasonable than taking a metabolic poison to inhibit the production of cholesterol and/or lipoproteins on a cellular level. If we feel we must abide by largely drug industry-determined lipid guidelines, e.g. keeping LDL below 100 mg/dl, natural substances like policosanol or red yeast rice can "do the job" quite effectively. In fact, we have collected research on over 100 natural substances with lipid lowering properties.
I am far more interested in the broad range of factors that contribute to atherosclerosis than simply suppressing cholesterol/lipoprotein levels through the "by any chemical means necessary" approach. To view all the sections on our database relevant to cardiovascular health in one place, along with plenty of research on natural substances and therapies which contribute to preventing these factors from adversely affecting our health, visit our Heart Health Research Center.

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Do you or someone you know take statin drugs? Are you aware of how statin drugs deplete the body of Coenzyme Q10?  If not, you need to read this...

It is well-established that statin drugs such as Lipitor not only inhibit the biosynthesis of cholesterol but also that of CoQ10.
This is a huge problem.
Here is a short quote from the 2007 PDR - Physician's Desk Reference - of observed Lipitor side effects:
"Body as a Whole: Chest pain, face edema, fever, neck rigidity, malaise, photosensitivity reaction, generalized edema.

Digestive System: Nausea, gastroenteritis, liver function tests abnormal, colitis, vomiting, gastritis, dry mouth, rectal hemorrhage, esophagitis, eructation, glossitis, mouth ulceration, anorexia, increased appetite, stomatitis, biliary pain, cheilitis, duodenal ulcer, dysphagia, enteritis, melena, gum hemorrhage, stomach ulcer, tenesmus, ulcerative stomatitis, hepatitis, pancreatitis, cholestatic jaundice.

Respiratory System: Bronchitis, rhinitis, pneumonia, dyspnea, asthma, epistaxis.

Nervous System: Insomnia, dizziness, paresthesia, somnolence, amnesia, abnormal dreams, libido decreased, emotional lability, incoordination, peripheral neuropathy, torticollis, facial paralysis, hyperkinesia, depression, hypesthesia, hypertonia.
Musculoskeletal System: Arthritis, leg cramps, bursitis, tenosynovitis, myasthenia, tendinous contracture, myositis.

Skin and Appendages: Pruritus, contact dermatitis, alopecia, dry skin, sweating, acne, urticaria, eczema, seborrhea, skin ulcer.....................
......................
Special Senses: Amblyopia, tinnitus, dry eyes, refraction disorder, eye hemorrhage, deafness, glaucoma, parosmia, taste loss, taste perversion.

Cardiovascular System: Palpitation, vasodilatation, syncope, migraine, postural hypotension, phlebitis, arrhythmia, angina pectoris, hypertension........"



This list of side effects goes on and on. It appears that any symptom under the sun as possible.
You may now begin to understand and appreciate why the depletion of CoQ10 can and will affect all aspects of our physical and mental/emotional life.
Without adequate levels of CoQ10 the cells of your body cannot do what they were designed to do. That is true for:
  • the cells of your brain
  • the cells of your heart
  • the cells of your muscles
  • the cells of your digestive system
  • the cells of your immune system
  • all cells of your body
Learn more about Heart Health Advanced Co-Q10



If you are a healthcare provider or a patient who would like to receive nutritional counseling, please call Beth Black at Orlampa Enterprises, Inc. at (727) 492-8212.

Orlampa Enterprises is an internet based product broker specializing in personalized health and wellness related services. Orlampa Enterprises is primed to continue its growth by duplicating its successful business model of educating, training, and developing entrepreneurial leaders as business partners. As an Unfranchise™ business owner, Orlampa Enterprises, proudly utilizes highly researched products including Isotonix® nutritional supplements. Orlampa Enterprises is a privately held company based in Trinity, Florida.  


Orlampa Enterprises' motto is "Eat well, exercise, and supplement intelligently."

Contact bb@orlampa.com for more information about independent Unfranchise™ business partnership opportunities available.
 




Sunday, July 1, 2012

Astaxanthin: A Rising Star in Alzheimer's Prevention

Courtesy ofMercola.com
By Dr. Mercola
In the United States, someone develops Alzheimer's disease every 69 seconds, and by 2050 this is expected to increase to a new case every 33 seconds, according to the Alzheimer's Association's 2011 Alzheimer's Disease Facts and Figures.
The disease is currently at epidemic proportions, with 5.4 million Americans—including one in eight people aged 65 and over—living with Alzheimer's disease.
By 2050, this is expected to jump to 16 million, and in the next 20 years it is projected that Alzheimer's will affect one in four Americans. If that comes to pass, it would then be more prevalent than obesity and diabetes is today!
Alzheimer's is a sad, devastating disease that develops slowly and gets worse over time. Worse yet, there is no known cure and very few treatments. Alzheimer's drugs are often of little to no benefit at all, which underscores the importance of prevention throughout your lifetime.
Alzheimer's develops over the course of a few decades, so the time to start preventing it is yesterday. Your approach to preventing this terrible disease should be a comprehensive lifestyle approach.
I will be discussing the most important aspects of this in a moment, but first, I would like to share new findings about one particular nutritional supplement that has scientists very excited in the battle against Alzheimer's disease.

Astaxanthin is a Rising Star in Alzheimer's Prevention

Astaxanthin is a natural pigment with unique properties and many clinical benefits, including some of the most potent antioxidant activity currently known. It is the same pigment that makes flamingos pink.
These birds are born with grey feathers—and after consuming their natural diet of astaxanthin-containing algae and crustaceans, they turn pink! It has been found to reduce the accumulation of phospholipid hydroperoxidases (PLOOH)—compounds known to accumulate in the red blood cells of people who suffer from dementia—and scientists now believe astaxanthin could help prevent dementia, including Alzheimer's.
As a fat-soluble nutrient, astaxanthin readily crosses your blood-brain barrier. One studyii found it may help prevent neurodegeneration associated with oxidative stress, as well as make a potent natural "brain food."
The molecules of astaxanthin neutralize free radicals and other oxidants without being destroyed or becoming pro-oxidants themselves in the process. It's is a unique molecule whose shape allows it to precisely fit into a cell membrane and span its entire width. In this position, astaxanthin can intercept potentially damaging moleculesbefore they can damage your cells.
In fact, astaxanthin is hundreds of times more effective than vitamin E in squelching singlet oxygen free radicals, and far exceeds the free radical scavenging power of vitamin C, CoQ10, beta-carotene, and green tea. According to a recent article in the Alternative Medicine Review:
"Astaxanthin improved cognition in a small clinical trial and boosted proliferation and differentiation of cultured nerve stem cells…   Astaxanthin's clinical success extends beyond protection against oxidative stress and inflammation, to demonstrable promise for slowing age-related functional decline."
This supports the findings of a prior 2011 study in the British Journal of Nutrition that showed taking 6 mg or 12 mg of astaxanthin daily for 12 weeks lowered levels of PLOOH by 40 percent and 50 percent, respectively.
It is unlikely you will be able to obtain enough astaxanthin from diet alone… unless you are a flamingo. You can get some astaxanthin by taking krill oil, which is a fantastic omega-3 fat supplement. But you can boost your astaxanthin even MORE by adding a pure astaxanthin supplement to your nutritional regimen.  For optimal absorption, make sure to take krill oil and/or astaxanthin with a fat-containing meal, since both are fat-soluble.

"Senior Moments" are NOT a Normal Part of Aging

In spite of how common memory loss is among Westerners, it is NOT a "normal" part of aging. Research has shown that even mild "senior moments" are caused by the same brain lesions associated with Alzheimer's disease and other forms of dementia. These cognitive changes are by no means inevitable! People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it's entirely possible to prevent the damage from occurring in the first place.

What Causes Alzheimer's Disease?

In order to effectively prevent a disease, you must address its underlying causative factors. Although we do not have definitive "proof" of what, specifically, causes Alzheimer's, a number of factors have been linked to an increased risk of dementia, and we know enough about those to in turn make educated recommendations for preventing this type of brain deterioration.
The more risk factors you have, the higher your changes are for developing dementia. You may already know I have become passionate about warning of the dangers of fructose. There is NO question in my mind that regularly consuming more than 25 grams of fructose per day will increase your risk of losing your mind.Fructose will catalyze the impact of virtually every other risk factor, like exposure to toxins such as aluminum, or mercury, or even genetic predispositions. It does this by impairing your body's normal self-repair capacity and its ability to recover from these types of assaults.
Following are a number of other factors associated with an increased risk of Alzheimer's disease. Please note that the first four are related to fructose intake.
Health conditions and drug therapies
  • Obesity, especially increased belly fat, insulin resistance, and diabetes: diabetics have up to 65 percent higher risk of developing Alzheimer's disease. Keep your fasting insulin level below 3 by minimizing sugar and grains and exercising regularly.
  • Elevated uric acid levels: fructose is one of the primary factors that drives up uric acid, which is another reason to avoid excess sugar.
  • High blood pressure.
  • Heart disease and atrial fibrillationiv: If you have "atrial fib," you are 44 percent more likely to develop dementia.
  • Thyroid dysfunction.v
  • Head traumavi: There appears to be a "strong link" between a history of head trauma and Alzheimer's disease, especially if the trauma occurred repeatedly or involved loss of consciousness—so keep your seat belt fastened.
  • Anticholinergic drugs: Drugs that block acetylcholine, a nervous system neurotransmitter, have been shown to increase your risk of dementia. These drugs include certain nighttime pain relievers, antihistamines, sleep aids, certain antidepressants, medications to control incontinence, and certain narcotic pain relievers.
  • One study found that those who took drugs classified as "definite anticholinergics" had a four times higher incidence of cognitive impairment. Regularly taking two of these drugs further increased the risk.
Nutritional deficiencies
  • Vitamin D deficiency: In 2007 researchers at the University of Wisconsin uncovered strong links between low levels of vitamin D in Alzheimer's patients and poor outcomes on cognitive tests. Vitamin D may enhance the levels of important chemicals in your brain that protect your brain cells and combat the brain inflammation seen in dementia patients.
    A 2011 study at UCLA found the combination of vitamin D3 and curcumin (the pigment that makes turmeric yellow) to be a highly beneficial combination for Alzheimer's patients.Vitamin D can also fight depression, which is experienced frequently by people with dementia.
  • Vitamin B deficiencies: Elevated homocysteine levels due to vitamin B6, B12 and folate deficiencies; according to a small Finnish study recently published in the Journal Neurology, people who consume foods rich in B12 may reduce their risk of Alzheimer's in their later years.
  • Insufficient omega-3 fats: High intake of the omega-3 fatty acid DHA lowers your risk for Alzheimer's by preventing the associated cell damage. Researchers also report that DHA "dramatically reduces the impact of the Alzheimer's gene."
  • Vitamin E deficiency: A 2008 study showed that Alzheimer's patients who took 2,000 IU of vitamin E daily showed a 26 percent lower mortality rate.
Environmental toxins
  • Aluminum toxicity: avoid antiperspirants, non-stick cookware, and vaccines containing aluminum (and mercury) adjuvants/additives, such as the flu vaccine
  • Mercury toxicity: Avoid fish and seafood, which is usually contaminated with mercury, and avoid dental amalgams, which are probably the largest sources of mercury; implement the mercury detox protocol and utilize a biological dentist if you have dental amalgams
  • Fluoride toxicity: More than 23 different studies indicate even moderate fluoride exposure may have damaging effects on your brain
  • Copper toxicity: Evidence exists that copper can leach out of copper pipes and into tap water, and when consumed over time, can build up in your body. Copper toxicity has been linked to Alzheimer's disease, heart disease, and diabetes. You should also avoid vitamin/mineral pills that contain copper and iron, especially if you're over the age of 50
  • Cell phone radiation. Radiation from cell phones and mobile phone handsets may damage areas of your brain associated with learning, memory and movement, and may trigger Alzheimer's disease

Exercise Your Body, Exercise Your Brain

Clearly, the BEST way to "treat" Alzheimer's is to lead a lifestyle that will prevent it in the first place. John J. Ratey, a psychiatrist who wrote the book Spark: The Revolutionary New Science of Exercise and the Brain, says there is overwhelming evidence that regular exercise helps fight dementia and improves mental acuity. Physical exercise may also protect against mild cognitive impairment by:
  • Promoting production of nerve-protecting compounds
  • Increasing blood flow to your brain
  • Improving development and survival of neurons
  • Promoting essential cell and tissue repair mechanisms, including growth of new brain cells
  • Decreasing your risk of heart and blood vessel diseases that can impact brain function
In essence, exercise encourages your brain to work at optimum capacity by causing your nerve cells to multiply, strengthening their interconnections, and protecting them from damage. Exercising your mind daily is as important as exercising your body, so be sure to incorporate some mentally challenging activities into your life, such as playing an instrument, doing puzzles, reading, or other similar activities.

Natural Treatments for Your Anti-Alzheimer's Arsenal

Finally, there are a few other nutritional recommendations worth noting for their specific benefits in preventing and treating dementia. So, although your fundamental strategy for preventing dementia should involve a comprehensive lifestyle approach, you may want to consider adding a few of these natural dietary agents to your anti-Alzheimer's arsenal.
The three natural foods/supplements that have good science behind them, in terms of preventing age-related cognitive changes, are coconut oil, Gingko biloba, and alpha lipoic acid.
  1. Coconut Oil: The primary fuel your brain needs for energy is glucose. However, your brain is able to run on more than a single type of fuel, one being ketones (ketone bodies), or ketoacids. Ketones are what your body produces when it converts fat (as opposed to glucose) into energy.
  2. The medium chain triglycerides (MCT) found in coconut oil are GREAT source of ketone bodies, because coconut oil is about 66 percent MCTs.In fact, ketones appear to be the preferred source of brain food in patients affected by diabetes or Alzheimer's.
  3. Gingko biloba: Many scientific studies have found that Ginkgo biloba has positive effects for dementia. Gingko, which is derived from a tree native to Asia, has long been used medicinally in China and other countries. Fifteen years ago, in one of the first issues of my newsletter, I posted the results of a 1997 study from JAMAx that showed clear evidence that Ginkgo improves cognitive performance and social functioning for those suffering from dementia. Research since then has been equally promising.
    One study in 2006 found Gingko as effective as the dementia drug Aricept (donepezil) for treating mild to moderate Alzheimer's type dementia. A 2010 meta-analysisxi found Gingko biloba to be effective for a variety of types of dementia.
  4. Alpha lipoic acid (ALA): ALA can stabilize cognitive functions among Alzheimer's patients and may slow the progression of the disease.

Thursday, February 16, 2012

What's Up With Curcumin

What's Up With Curcumin?
Phillip A. Black

Curcumin. What is that? Do you know anything about it? Have you seen the headlines lately? The following are all articles published within the past few days about curcumin.
Wow. Intrigued? I know I was when I was first introduced to this amazing product about three years ago. I am going to do my best to quickly bring you up to speed about curcumin.
Per Wikipedia, "curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are natural phenols and are responsible for the yellow color of turmeric." Great. But what does that all mean? It means this is one heck of a spice!
For thousands of years Eastern medicine has used curcumin for a wide range of health benefits. However, western medicine was late to arrive at the party. A wealth of recent scientific data shows curcumin to contain powerful anti-inflammatory, anti-tumor and antioxidant properties.

Unlike many pharmaceuticals, curcumin has been proven safe without any adverse affects, even at doses up to 8,000 mg/day. Extensive research shows curcumin is effective in multiple ways, and this provides basis for many applications. But curcumin is extremely difficult to absorb, so it's important to get an ample supply of it into your bloodstream.

There are more than 4,300 published studies describing curcumin’s benefits in helping to fight cardiovascular disease, Alzheimer’s disease, cancer, osteo and rheumatoid arthritis, liver disease, renal failure, depression, asthma, Crohn’s disease, psoriasis, infections (including pneumonia) and diabetes—and this list is not all-inclusive. What all these diseases have in common is that they encompass inflammation, oxidative stress and inactive genetic expression.

A research team at Thomas Jefferson University found that curcumin may help slow down tumor growth in castration-resistant prostate cancer patients who are on androgen deprivation therapy. To help support their findings, the researchers also investigated curcumin in mice, which were castrated to mimic ADT. Tumor growth and masses were significantly reduced in the mice with curcumin. Researchers feel the study also has implications beyond prostate cancer, offering hope for alternatives of breast cancer. The study is published in the latest edition of the journal Cancer Research.

I think it's pretty clear that curcumin is something we should all consider taking.









CURCUMIN EXTREME
TM


Primary Benefits of Curcumin Extreme™*:
  • Promotes normal activity of NF-KappaB
  • Supports normal liver detoxification activity
  • Supports overall liver health
  • Promotes apoptosis in unhealthy cells
  • Promotes normal cell cycle activity
  • Helps maintain overall cell integrity
  • Promotes normal cellular regeneration
  • Helps maintain healthy glutathione levels
  • Supports normal glutathione synthesis
  • Promotes the normal production of detoxification enzymes
  • Supports the body’s natural ability to produce detoxification enzymes
  • Promotes normal levels of detoxification enzymes that scavenge harmful toxins in the body
  • Helps to maintain neurological health as we age
  • Helps to maintain good cognitive health as we age
  • Promotes normal immune cell-brain (neuron) interactions in order to maintain cognitive health
  • Promotes neurological health
  • Protects neurons from the negative effects of free radicals
  • Powerful antioxidant
  • Protects the body from the negative effects of free radicals
  • Promotes free-radical protection
  • Promotes a strong immune system
Key Ingredients Found In Curcumin Extreme™:

Curcumin (BCM-95®): 400 mg
Scientists have long been aware of the wide array of health benefits from the Indian spice turmeric, which is a source of the active phytochemical curcumin. Until now, curcumin has been known to have poor bioavailability, requiring high doses to promote health. BCM-95® delivers significantly more pharmacologically bioactive curcumin into the blood than other curcumin sources. This new delivery system allows for a variety of health benefits.
How is this possible? Traditional 95% extract focuses strictly on one part of the Turmeric rhizome. This bioactive substance of Turmeric (Curcuma Longa) contains “Curcuminoids” and Curcumin is the most important molecule. Research has shown its tremendous health benefit. Even though Curcumin is the most important molecule, the bioavailability of the regular Turmeric 95% extracts sold on the market is not very good in terms of uptake or sustainability in the blood stream. There are other essential components present in Turmeric Rhizome which have been neglected during the traditional method of manufacturing of Turmeric 95% Extract. BCM-95® represents the natural spectrum of turmeric rhizome. It is 100 percent natural and has been proven to provide optimal bioavailability for synergistic effect. This new method of manufacture offers tremendous value in terms of bioavailability.
Antioxidants have received increased attention, and it’s important to know what nutrients are antioxidants and information about them. One such nutrient is Curcumin. Curcumin is a natural extract from the spice turmeric. Turmeric is derived from the plant Curcuma Longa, a member of the ginger family.
Curcumin is employed mostly as an antioxidant; though it was traditionally used to promote stomach and joint comfort. The immune-balancing activity of curcumin has been demonstrated through multiple mechanisms to support normal COX-2 and NF-KappaB levels in the body.
The neuroprotective properties of curcumin are among the most studied. Curcumin has been designated as a strong candidate for the promotion of neurological health and cognitive function. Curcumin can cross the blood-brain barrier and support the normal uptake of amyloid-beta in the brain. This supports the brain's memory and learning abilities as we age. Another neuroprotective property of curcumin is its ability to promote normal levels of glutathione, superoxide dismutase and catalase in the brain. This can help to maintain the health of neurological tissues.
Curcumin supports the normal production of Phase II liver detoxification enzymes including glutathione synthase, heme-oxygenase and catalase. The liver plays several roles in detoxification: it filters the blood to remove large toxins, synthesizes and secretes bile full of cholesterol and other fat-soluble toxins, and enzymatically disassembles unwanted chemicals. This enzymatic process usually occurs in two steps referred to as phase I and phase II. They promote the body’s natural enzyme antioxidant defense systems and function as a powerful indirect antioxidant. These enzymes promote the body’s normal metabolism of harmful chemicals such as heavy metals, toxins and pollutants into less reactive molecules. Curcumin has also been shown to promote normal hepatic tissue repair.Broccoli Seed Extract (6% Sulphoraphane Glucosinolates): 167 mgThe health benefits and protective properties of broccoli and other cruciferous vegetables have been well documented over the past 25 years. Broccoli Seed Extract is a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of Phase II liver detoxification enzymes including glutathione synthase, heme-oxygenase and catalase. Sulforaphanes promote the body’s natural enzyme antioxidant defense systems and function as a powerful indirect antioxidant. Sulphoraphanes work to support gene transcription, which is the process by which genetic information is copied from DNA to RNA, resulting in a specific protein formation. Conclusively, sulphoraphanes work to support the body’s natural defense systems and to maintain elevated levels of glutathione.
Glutathione is the master antioxidant of the body. It is an important chemical that acts as a powerful antioxidant to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. It also acts to recycle vitamin C and E, which also reduce free radicals. Since glutathione cannot be absorbed intact orally due to gastrointestinal degradation, sulphoraphane supplementation may be the most effective way to increase endogenous glutathione concentration.Selenium (Selenomethionine): 100 mcgSelenium is a required cofactor for selenoproteins such as glutathione peroxidase. Selenomethionine is incorporated directly into proteins because selenomethionine cannot be distinguished from methionine during the translation of mRNA into protein. This serves as a storage form of selenium and is liberated upon protein catabolism. Selenium accumulates in the prostate, promoting the health of the prostate. Selenium supports immune function by promoting normal growth and development of T helper cells.


Scientific Studies Which Support Curcumin Extreme™:
  • Araujo, C. and Leon, L. Biological activities of Curcuma longa L. Memorias do Instituto Oswaldo Cruz. 96(5): 723-728, 2001.
  • Bhattacharyya, S., et al. Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction. Journal of Biological Chemistry. 282(22): 15954-15964.
  • Biswas, S., et al. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxidants and Redox Signaling. 7(1-2): 32-41, 2005.
  • Cheng, Y., et al. Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells. Chinese Medical Journal. 120(9): 794-801, 2007.
  • Churchill, M., et al. Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile. Journal of Surgical Research. 89(2): 169-175, 2000.
  • Cornblatt, B., et al. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. 28(7): 1485-1490, 2007.
  • Dairam, A., et al. Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. Journal of Agricultural and Food Chemistry. 55(3): 1039-1044, 2007.
  • Dickinson, D., et al. Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression. FASEB. 17(3): 473-475, 2003.
  • Fahey, J., et al. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proceedings of the National Academy of Sciences of the United States of America. 99(11): 7610-7615, 2002.
  • Farombi, E., et al. Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food and Chemical Toxicology. 46(4): 1279-1287, 2008.
  • Funk, J., et al. Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. Journal of Natural Products. 69(3): 351-355, 2006.
  • Gao, X. and Talalay, P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proceedings of the National Academy of Sciences of the United States of America. 101(28): 10446-10451, 2004.
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What Makes Curcumin Extreme™ Unique?
There are many curcumin products on the market, but Curcumin Extreme™ with BCM-95® has superior bioavailability and absorption. BCM-95 contains the natural spectrum of the turmeric rhizome and is 100 percent natural. Curcumin Extreme promotes liver detoxification, promotes healthy glutathione levels and normal cellular regeneration. Taking Curcumin Extreme every day can help detoxify impurities in your body that build up over time.*
Curcumin Extreme also includes 167mg of broccoli seed extract, a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of Phase II liver detoxification enzymes, including glutathione synthase, heme-oxygenase and catalase. Sulforaphanes also support gene transcription, the process by which genetic information is copied from DNA to RNA. They also support the body’s natural defense systems. Glutathione is the master antioxidant in the human body, which serves to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. Furthermore, glutathione recycles vitamins C and E, which are also powerful antioxidants.*


Frequently Asked Questions About Curcumin Extreme™:
What is Curcumin?
Curcumin is present in the spice turmeric, frequently used in Indian food. Its chemical makeup is responsible for the yellow coloring of turmeric and is often used specifically to give color to foods. However, it may serve a more important purpose to humans.
Are any side effects associated with Curcumin Extreme™?
Side effects are uncommon and are generally limited to mild stomach distress.
What are the potential advantages of taking curcumin?
Curcumin supports liver detoxification activity, promotes normal cellular regeneration and helps maintain healthy glutathione levels. It also supports the body’s natural ability to produce detoxification enzymes and has been shown to be a powerful antioxidant. It promotes neurological health and helps to maintain neurological health as we age. It can also promote free radical protection and a strong immune system.*
Are there any warnings associated with taking Curcumin Extreme?
If you are currently taking warfarin (Coumadin) or other anti-platelet/anti-coagulate, you should not take this product. If you are taking any other prescription drugs or have an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or breastfeeding should not take this product.
Who should take Curcumin Extreme?
Anyone 18 or over can take Curcumin Extreme, especially those who want to support their normal liver detoxification activity, help maintain their healthy glutathione levels, promote their neurological health and those who want to promote a strong immune system.
What other Market America products work well with Curcumin Extreme?
Curcumin Extreme can be taken in conjunction with Glucosatrin® to support normal COX-2 levels and promote joint comfort. It can also be taken with Cognitin™ to promote normal immune cell-brain (neuron) interactions in order to maintain cognitive health and also to promote neurological health.
Can I take OPC-3® with Curcumin Extreme?
Yes, as long as the directions for use are followed for each product.
I am considering purchasing Curcumin Extreme because of some of the positive effects that I have read about. Should I refrain from taking my medications while taking curcumin or can I take both?If you are taking any prescription drugs or have an ongoing medical condition, you should consult your physician before using this product. Your physician can properly advise you about the best course of action regarding your prescription medications.
What is the recommended daily serving for Curcumin Extreme?
Take 1 capsule per day with or without a meal.
Are there any human clinical trials done with Curcumin?
There have been clinical trials performed with curcumin in patients with different diseases. These are mostly pilot studies that are “proof of concept” type. More than 10 trials are now in progress in the United States and other countries.
What is the purpose of the Broccoli Seed Extract contained in this product?
It promotes the liver detoxification activity, and it works to support the body’s natural defense systems and to sustain elevated levels of glutathione.
Can men and women take this product?
Yes. However, women who are pregnant or breastfeeding should not take this product.
Does Curcumin Extreme contain any allergens?
No, the product is free from any allergens such as soy, wheat, gluten or dairy.
When should I start to see/feel the effects of this product? What should I expect?The antioxidant benefits of Curcumin should be noticeable in about four to six weeks. Please remember that everyone’s body is different, so for some it may take longer to notice the benefits of Curcumin. You should expect to feel better and healthier overall.*




These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease