While not recommending that patients abandon their inhalers, Italian researchers report that daily supplements of the pine bark extract may help asthma patients reduce inhaler dosage and sleep awakenings.
"The outcome (of the study) does indeed point to the possibility to allow asthmatic patients to moderately reduce their daily inhaled fluticasone dose," wrote Dr. Gianni Belcaro, the study's lead researcher. Asthmatic patients are reminded that they should always have access to their inhaler.
Writing in Panminerva Medica, researchers from the University of Pescara, Italy, report that daily supplementation with Pycnogenol allowed for lowering the daily required inhaled corticosteroid (ICS) dosage in 55% of participants.
Only six percent of people in the study control group were able to control their asthma with a lower steroid dosage while 19% had to switch to a higher regimen to control their asthma.
"This study gives promising news to asthma patients seeking natural ways to complement their medication in order to better control their asthma symptoms, and confirms that Pycnogenol offers a natural solution that is not only effective but also safe," said Dr. Belcaro.
Pycnogenol—a combination of procyanidins, bioflavonoids and organic acids extracted from the bark of the maritime pine—has been the subject of scores of clinical trials.
The new study involved 76 people with mild to moderate allergic asthma. The participants were randomly divided into one of two groups: The first group received 100 mg of Pycnogenol per day in addition to sustaining their use of ICS, while the other group continued their use of ICS without additional supplementation.
After six months of intervention, the researchers observed that the use of a salbutamol rescue inhaler was required, on average, every fifth day in the Pycnogenol group, whereas such inhalers were required, on average, every second day in the control group.
In addition, the pine bark group reported fewer night awakenings caused by asthma symptoms—only half the frequency as before—while no significant change was found for the control group, said the researchers.
"The decrease of typical asthma symptoms with coughing, wheezing, dyspnea and nighttime awakenings suggests that Pycnogenol may contribute to improving quality of life of patients suffering from asthma," wrote Dr. Belcaro and his co-workers.
"Further studies are warranted to corroborate the benefits in a larger population, which may be necessary to create sufficient awareness and confidence in the medical community of the adjuvant virtues of Pycnogenol."
Panminerva Medica 53(3Suppl 1):57-64, 2012
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nutraMetrix Isotonix® OPC-3®Key Ingredients Found In nutraMetrix Isotonix OPC-3®:
Pine Bark Extract (Pycnogenol®): 25 mg
Pycnogenol is a natural plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. This unspoiled and natural forest environment is the unique source of pine bark. Pycnogenol is one of the most researched ingredients in the natural product marketplace. Published findings have demonstrated Pycnogenol’s wide array of beneficial effects on the body. Pine bark extract is an all natural combination of procyanidins, bioflavonoids and organic acids.
The
extract has three basic properties — it is a powerful antioxidant,
selectively binds to collagen and elastin, and promotes the normal
production of endothelial nitric oxide, which promotes the normal
dilation of dilate blood vessels.*
As
one of the most potent natural scavenger of free radicals, Pycnogenol
combats many aggressive free radicals before they cause oxidative stress
to vital organs. Its super-antioxidant capabilities help support
healthy blood platelet activity, support healthy blood glucose levels,
reduce mild menstrual cramping and abdominal pain, maintain joint
flexibility, promote cardiovascular health, promote healthy sperm
quality, maintain healthy cholesterol levels and support a healthy
complexion.*
Grape Seed Extract: 25 mg
Grape seed extract is typically extracted from the seeds of red grapes (instead of white), which have a high content of compounds known as oligomeric proanthocyanidins (OPCs). Grape seed extract is extremely rich in polyphenols, compounds with high antioxidant activity. Grape seed extract has been found to maintain healthy cholesterol levels.* Red Wine Extract: 25 mg Red wine extract is a powerful antioxidant. This extract is found in grape vines, roots, seeds and stalks, with the highest concentration in the skins. The antioxidant properties of red wine extract contribute to maintaining healthy circulation by strengthening capillaries, arteries and veins, and promoting overall cardiovascular health.*
In
the late 1990s, scientists took note of a phenomenon among the
French. There were very low rates of cardiovascular problems in the
provinces where residents consistently ate high fat foods and drank red
wine. Scientists concluded that the protective properties of red wine
have helped the French maintain cardiovascular health for years and
subsequent scientific studies have further shown that the OPCs found in
red wine are particularly beneficial for protecting the heart and blood
vessels.*
Bilberry Extract: 25 mg
Bilberry extract is derived from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins, which are powerful antioxidants. Scientific studies confirm that bilberry extract supports healthy vision and venous circulation. Bilberry extract helps maintain healthy circulation by strengthening capillaries, arteries and veins.*
Citrus Extract (Bioflavonoids): 25 mg
Bioflavonoids are antioxidants found in certain plants that act as light filters, which protect delicate DNA chains and other important macromolecules by absorbing ultraviolet radiation. They have been found to promote cardiovascular health, help maintain healthy circulation by strengthening capillaries, arteries and veins, and demonstrate anti-inflammatory activity.*
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